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AlmightyDoorman
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Cake day: June 1st, 2025
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2·1 month agoAhh okay, the headline implied that for me but you are both correct that it does not outright say so.
Did we read the same article? The point is that for some people it resulted in no viral load even without drugs over a prolonged time.
In a study published last year, Goulder described how all five remained in remission, despite having not received regular antiretroviral medication for some time, and in one case, up to 17 months. In the decadeslong search for an HIV cure, this offered a tantalizing insight: that the first widespread success in curing HIV might not come in adults, but in children.
Instead, like Goulder, pediatricians have increasingly noticed that after starting antiretroviral treatment early in life, a small subpopulation of children then seem able to suppress HIV for months, years, and perhaps even permanently with their immune system alone.
12·2 months agoKlinefelter cats can have the same fur patterns while phenotypical presenting as male. Very unlikely though.
Can’t read the whole article due to paywall. Here are 2 thoughts for the half that i did read.
colorectal cancer makes a lot of sense as a target. it still is one of the most cancers with the highest mortality. At the same time we saw an uptick in colorectal cancer rates in young people (reason unknown, maybe microplastics maybe something else.). Furthemore colorectal cancer seems to be a great target for immunsystem modulating therapy. There was a paper 3 years bake in I think the NEJM where they put 18/18 (exact N not sure) patients in remission with PD-1 modulation which also activates the immun system.
Astra Zeneca (I believe) is also working on a mRNA vaccine for cancer that is quite far along. They are targeting melanoma in remission and reduced reoccurence of melanoma or metastasis after 3 years by 50%. So it seems like mRNA cancer vaccines will be a strong pillar for future cancer treatements.
Sadly we saw in the past that russia sometimes bolsters their numbers for medication efficency. I hope it is not the case this time but i hope that the phase 2/3 trials will be very transparent to quench any doubts.