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1, it’s aspartame
2, Mice aren’t humans, and routinely, things that happen in mice do not happen in humans. It is not at all indicative of anything and can really only be used as a hint better than nothing for looking into similar effects in humans.
You don’t need to change your diet, and you certainly don’t need to replace it with sugar.
Removing all forms of added sugar would probably make everyone feel better. Even minimizing natural sugar intake.
Sugar is terrible, there’s no doubt about it. Artificial or otherwise.
Absolutely nothing wrong with a diet high in fruit and veg, both of which contain significant amounts of sugar.